Before the first astronaut was launched into space, scientists and engineers had to determine if it was even possible for the human body to function in zero-g. This video reviews some of the instruments and techniques developed at the NASA Johnson Space Center’s Life Sciences Directorate. Included are some of the early tests which were conducted, such as the centrifuge and bed-rest studies, as well as developments in remote medical care capabilities. Also included is a look at the benefits of these medical developments of health services on Earth and a preview of possible future developments in life sciences.